MOQ:10g
Price:10-15usd/g
Customization:Customized
Packaging Details:foil bag or as you request
Payment Terms:T/T, Bitcoin
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Product Name:GW0742
CAS:317318-84-6
Synonyms GW0742;[4-[[[2-[3-FLUORO-4-(TRIFLUOROMETHYL)PHENYL]-4-METHYL-5-THIAZOLYL]METHYL]THIO]-2-METHYLPHENOXY]ACETIC ACID;4-[2-(3-FLUORO-4-TRIFLUOROMETHYL-PHENYL)-4-METHYL-THIAZOL-5-YLMETHYLSULFANYL]-2-METHYL-PHENOXY-ACETIC ACID;4-[[[2-[3-Fluoro-4-(trifluoromethyl)phenyl]-4-methyl-5-thiazolyl]methyl]thio]-2-methylphenoxy]AceticAcid;4-[2-(3-Fluoro-4-trifluoromethyl-phenyl)-4-methyl-thiazol-5-ylmethylsulfanyl]- 2-methyl-phenoxy}-acetic acid;Acetic acid, 2-[4-[[[2-[3-fluoro-4-(trifluoroMethyl)phenyl]-4-Methyl-5-thiazolyl]Methyl]thio]-2-Methylphenoxy]-;2-(4-(((2-(3-Fluoro-4-(trifluoromethyl)phenyl)-4-methylthiazol-5-yl)methyl)thio)-2-methylphenoxy);GW 0742X
Purity:99%
MF:C21H17F4NO3S2
MW:471.49
mp:134.5-135.5 °C
GW0742, also known as GW610742, is a PPAR agonist. GW0742 Induces Early Neuronal Maturation of Cortical Post-Mitotic Neurons. GW0742 prevents hypertension, vascular inflammatory and oxidative status, and endothelial dysfunction in diet-induced obesity. GW0742 has direct protective effects on right heart hypertrophy.GW0742 may enhance lipid metabolism in heart both in vivo and in vitro.
GW0742 activates AMP-activated protein kinase and stimulates glucose uptake in skeletal muscle tissue , and GW501516 has been demonstrated to reverse metabolic abnormalities in obese men with pre-diabetic metabolic syndrome , most likely by stimulating fatty acid oxidation.
GW0742 has been proposed as a potential treatment for obesity and related conditions , especially when used in conjunction with a synergistic compound AICAR , as the combination has been shown to significantly increase exercise endurance in human.
