Quick Details:
Product name: Poudre de tétracaïne,Amethocaine
Synonyms: 2-(Dimethylamino)ethyl 4-(butylamino)benzoate; 2-(Dimethylamino)ethyl p-(butylamino)benzoate; 2-Dimethylaminoethylester kyseliny p-butylaminobenzoove: 2-dimethylaminoethylesterkyselinyp-butylaminobenzoove; 2-dimethylaminoethylp-butylaminobenzoate; 4-(butylamino)-benzoicaci2-(dimethylamino)ethylester: Amethocaine; Anetain
Category: Pharmaceutical raw materials
Le TAS: 94-24-6
L’EINECS: 202-316-6
Purity: 99.5% min
Molecular formula: C15H24N2O2
Molecular weight: 264.3633
Appearance: White powder
Poudre de tétracaïne Description:
Poudre de tétracaïne (INN, also known as amethocaine; trade name Pontocaine. Ametop and Dicaine) is a potent local anesthetic of the ester group. Tetracaine powder is mainly used topically in ophthalmology and as an antipruritic, and Tetracaine powder has been used in spinal anesthesia. Tetracaine powder is on the World Health Organization’s List of Essential Medicines, a list of the most important medication needed in a basic health system.
Tetracaine powder is indicated for the production of spinal anesthesia for procedures requiring two to three hours. Parenteral administration of Tetracaine powder stabilizes the neuronal membrane and prevents initiation and transmission of nerve impulses thereby effecting local anesthesia.
Poudre de tétracaïne Application:
In biomedical research, tetracaine powder is used to alter the function of calcium release channels (ryanodine receptors) that control the release of calcium from intracellular stores. Tetracaine powder is an allosteric blocker of channel function. At low concentrations, tetracaine powder causes an initial inhibition of spontaneous calcium release events, while at high concentrations, tetracaine powder blocks release completely.
Tetracaine powder is the T in Tac, a mixture of 5 to 12 percent tetracaine powder, 5% (per myriad), a half per mille (0.5%), or .05 percent (1 part in 2000) adrenaline, and 4 or 10 percent cocaine hydrochloride used in ear, nose & throat surgery and in the emergemcy department where numbing of the surface is needed rapidly, especially when children have been injured in the eye, ear, or other sensitive locations.
